氯吡格雷是临床常用的抗血小板聚集药之一,它通过选择性抑制二磷酸腺苷与血小板受体的结合,阻断二磷酸腺苷介导的血小板活化,从而发挥抗血小板、抗血栓形成的作用,常用于预防和治疗急性心肌梗死、脑卒中、冠心病等心脑血管疾病。
参考文献:SMART-CHOICE 3 investigators. Efficacy and safety of clopidogrel versus aspirin monotherapy in patients at high risk of subsequent cardiovascular event after percutaneous coronary intervention : a randomised, open-label, multicentre trial. Lancet. 2025 Mar 28:S0140-673600449-0.